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40-1152-U500-500 µg - Anti-CSF1R Rat Monoclonal Antibody [Clo


40-1152-U500-500 µg - Anti-CSF1R Rat Monoclonal Antibody [Clo


Product description

The AFS98 antibody is specific for mouse CD115, also known as Colony-Stimulating Factor-1 Receptor (CSF-1R), a 145 kDa receptor from the PDGF receptor family. Receptor activation by the ligands IL-34 or CSF-1 (M-CSF) occurs via homodimerization of CD115 and subsequent tyrosine phosphorylation and ubiquitination of intracellular domains. CD115 signaling promotes differentiation of myeloid precursors, as well as the continued regulation of proliferation, survival and function of mononuclear phagocytes, dendritic cells and osteoclasts. While IL-34 and CSF-1 may induce similar cellular responses, they are differentially expressed and as such exert complimentary actions via CD115. The AFS98 antibody may be used for identification of myeloid lineage cells by flow cytometry, and is commonly used for in vivo or in vitro neutralization of CSF-1 Receptor. Type: PrimaryAntigen: CSF1RClonality: MonoclonalClone: AFS98Conjugation: Epitope: Host: RatIsotype: Reactivity:

40-1152-U500-500 µg - Anti-CSF1R Rat Monoclonal Antibody [Clo

Water Treatment Solutions

Lenntech Water Treatment solutions is a design and manufacturing company serving numerous industries.
Since 1993, we’ve been delivering innovative and sustainable solutions for several applications and processes of water treatment, wastewater reuse and membrane separation.
Our wide range of technologies and extended know-how in all water-related sectors will guarantee you a cost-efficient solution meeting your water quality requirements.


Aquatech  -  Lenntech, The Winner of the Innovation Award

Closed Circuit Reverse Osmosis


UF Membranes

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